Karl J. Smalley, B.B.A.


Database Administrator,
Informatics Shared Resource


Sidney Kimmel Cancer Center

SKCC Affiliate Member

Relational Databases, Computer Programming, and Statistics

CV/Resume

Phone (Google VoiceMail)
(484) 238-0525

Office Address
504 BLSB
233 S. 10th Street
Philadelphia, PA 19107

Email Address
Karl.Smalley@jefferson.edu

 

Mr. Karl J. Smalley is interested in the development of Relational Database Applications, Computer Programming and Applied Statistics. He developed several web-based reservation/on-line billing systems for SKCC Shared Resources. He developed a web-based result download applications for both the Nucleic Acid Facility and the Microarray Facility. He also developed most of the department specific Administrative Applications which were used for various periods of time by the SKCC, the Department of Cancer Biology, the Department of Microbiology and Immunology, Department of Pharmacology and Department of Medical o­ncology at Thomas Jefferson University. He developed a web-based, protocol driven, weight based Chemotherapy Medication Ordering System for the TJUH Pharmacy. He developed multi-user Mouse Allele Database application in Oracle & C for tracking/recording genetic drift. Developed a document distribution application for the Sidney Kimmel Cancer Network, to allow fast and efficient dispersal of documents pertaining to active clinical trial protocols. He assisted in the development and maintenance of the electronic serious adverse event tracking system (eSAEy). developed and maintains the electronic Unanticipated Problem Reporting system (eazUP) and developed and maintains the electronic submission application (Portal) or the TJU Department of Human Research. Has developed/maintained applications which present various subsets of Clinical Trails information to the Senior Leadership, clinicians and patients (originally from an in-house CTMS product which he helped develop and more recently from the Forte onCore CTMS). He has helped researchers with graphics design and basic statistical analysis. He is responsible for producing several Data Tables for the SKCC CCSG application. He has also been involved in the Informatics Shared Resource's caBIG projects.Previously, He also helped SKCC researchers with their computing needs (maintenance, purchasing, etc.). Developed SMART (SKCC Member Administrative Reporting Tool - fka CCSGPubs) application to collect and report SKCC publications and grant funding in CCSG Grant applications. Re-wrote and maintained the Tumor Measurement Request Application for oncology clinical trials that require radiological assessment of tumor progression during trial.


Keywords: computers, relational databases, programming, statistics
 

PubMed Link For Smalley KJ

Publications

31.   Fong LY, Huebner K, Jing R, Smalley KJ, Brydges CR, Fiehn O, Farber JL, Croce CM. Zinc treatment reverses and anti-Zn-regulated miRs suppress esophageal carcinomas in vivo. Proc Natl Acad Sci U S A. 2023 May 16;120(20):e2220334120. Epub 2023 May 8. PMID: 37155893 PMCID: PMC10193985 DOI: 10.1073/pnas.2220334120 ( Abstract ) Google Scholar Citation Count: 2 (03/28/0024) iCite Citation Count: 1 and iCite RCR: (03/01/2024)

30.   Fong LY, Taccioli C, Palamarchuk A, Tagliazucchi GM, Jing R, Smalley KJ, Fan S, Altemus J, Fiehn O, Huebner K, Farber JL, Croce CM. Abrogation of esophageal carcinoma development in miR-31 knockout rats. Proc Natl Acad Sci U S A. 2020 Mar 17;117(11):6075-6085. PMID: 32123074 PMCID: PMC7084137 DOI: 10.1073/pnas.1920333117 ( Abstract ) Google Scholar Citation Count: 22 (03/28/0024) iCite Citation Count: 17 and iCite RCR: 1.37 (04/01/2024) OpenCitations Citation Count: 11 (04/01/2024)

29.   Fong LY, Jing R, Smalley KJ, Wang ZX, Taccioli C, Fan S, Chen H, Alder H, Huebner K, Farber JL, Fiehn O, Croce CM. Human-like hyperplastic prostate with low ZIP1 induced solely by Zn deficiency in rats. Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11091-E11100. PMID: 30397150 PMCID: PMC6255182 DOI: 10.1073/pnas.1813956115 ( Abstract ) Google Scholar Citation Count: 24 (03/28/0024) iCite Citation Count: 19 and iCite RCR: 0.89 (04/01/2024) OpenCitations Citation Count: 15 (04/01/2024)

28.   Fong LY, Jing R, Smalley KJ, Taccioli C, Fahrmann J, Barupal DK, Alder H, Farber JL, Fiehn O, Croce CM. Integration of metabolomics, transcriptomics, and microRNA expression profiling reveals a miR-143-HK2-glucose network underlying zinc-deficiency-associated esophageal neoplasia. Oncotarget. 2017 Oct 10; 8(47):81910-81925. PMID: 29137232 PMCID: PMC5669858 DOI: 10.18632/oncotarget.18434 ( Abstract ) Google Scholar Citation Count: 16 (03/28/0024) iCite Citation Count: 10 and iCite RCR: 0.41 (04/01/2024) OpenCitations Citation Count: 8 (04/01/2024)

27.   Fong LY, Taccioli C, Jing R, Smalley KJ, Alder H, Jiang Y, Fadda P, Farber JL, Croce CM. MicroRNA dysregulation and esophageal cancer development depend n the extent of zinc dietary deficiency. Oncotarget. 2016 Mar 8;7(10):10723-38. PMID: 26918602 PMCID: PMC4905434 ( Abstract ) Google Scholar Citation Count: 32 (03/28/0024) iCite Citation Count: 25 and iCite RCR: 1.04 (04/01/2024) OpenCitations Citation Count: 22 (04/01/2024)

26.   Taccioli C, Garofalo M, Chen H, Jiang Y, Tagliazucchi GM, Di Leva G, Alder H, Fadda P, Middleton J, Smalley KJ, Selmi T, Naidu S, Farber JL, Croce CM, Fong LY. Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo. J Natl Cancer Inst. 107(11):, 2015. PMID: 26286729 PMCID: PMC4675101 DOI: 10.1093/jnci/djv220 ( Abstract ) Google Scholar Citation Count: 40 (03/28/0024) iCite Citation Count: 34 and iCite RCR: 1.09 (04/01/2024) OpenCitations Citation Count: 32 (04/01/2024)

25.   Tacioli C, Chen H, Garoalo M, Jiang Y, Di Leva G, Alder H, Middleton J, Smalley KJ, Bottoni A, Costinean S, Farber JL, Croce CM, Fong LYY. Abstract/Poster Presentation: Silencng of miroRNA-31 Prevents Esophageal Neoplasia in Znc-Deficient Rats. American Association for Cancer Research, Washington DC, April 2013.

24.   Alder H, Taccioli C, Chen H, Jiang Y, Smalley KJ, Fadda P, Ozer HG, Huebner K, Farber JL, Croce CM, Fong LY. Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer. Carcinogenesis. 2012 Sep; 33(9): 1736-44. Epub 2012 Jun 10. PMID: 22689922 PMCID: PMC3514898 DOI: 10.1093/carcin/bgs204 ( Abstract ) Google Scholar Citation Count: 134 (03/28/0024) iCite Citation Count: 93 and iCite RCR: 2.92 (04/01/2024) OpenCitations Citation Count: 85 (04/01/2024)

23.   Taccioli C, Chen H, Jiang Y, Liu XP, Huang K, Smalley KJ, Farber JL, Croce CM, Fong LY. Dietary zinc deficiency fuels esophageal cancer development by inducing a distinct inflammatory signature. Oncogene. 2012 Oct 18; 31(42):4550-8. Epub 2011 Dec 19. PMID: 22179833 PMCID: PMC3310953 DOI: 10.1038/onc.2011.592 ( Abstract ) Google Scholar Citation Count: 83 (03/28/0024) iCite Citation Count: 61 and iCite RCR: 1.99 (03/01/2024) OpenCitations Citation Count: 54 (04/01/2024)

22.   Fong LY, Jiang Y, Rawahneh ML, Smalley KJ, Croce CM, Farber JL, Huebner K. Zinc supplementation suppresses 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis. Carcinogenesis. 2011 Apr; 32(4):554-60. PMID: 21245412 PMCID: PMC3066417 DOI: 10.1093/carcin/bgr004 ( Abstract ) Google Scholar Citation Count: 42 (03/28/0024) iCite Citation Count: 22 and iCite RCR: 0.75 (04/01/2024) OpenCitations Citation Count: 21 (04/01/2024)

21.   Fong LY, Jiang Y, Rawahneh ML, Smalley KJ, Croce CM, Farber JL, Huebner, K. Poster Presentation: Zinc Supplementation Suppresses 4-Nitroquinoline 1-Oxide-Induced Rat Oral Carcinogenesis. American Association for Cancer Research: Frontiers in Cancer Prevention, Philadelphia PA. November 2010.

20.   Wan SG, Taccioli C, Jiang Y, Chen H, Smalley KJ, Huang K, Liu XP, Farber JL, Croce CM, Fong LY. Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression. Int J Cancer. 2011 Jul 15; 129(2):331-45. PMID: 20857495 PMCID: PMC3015018 DOI: 10.1002/ijc.25688 ( Abstract ) Google Scholar Citation Count: 51 (03/28/0024) iCite Citation Count: 33 and iCite RCR: 0.95 (04/01/2024) OpenCitations Citation Count: 30 (04/01/2024)

19.   London JW, Smalley KJ, Chatterjee D, Isikoff JM, Housman D, Palchuk MB. Integration of caTissue with Clinical Data in an i2b2 Research Data Mart. Poster Presentation. CaBig Annual Meeting: Building a Collaborative

18.   London JW, Smalley KJ, Conner K, Smith JB. The automation of clinical trial serious adverse event reporting workflow. Clin Trials. 2009; 6(5):446-54. PMID: 19737847 PMCID: PMC3088507 DOI: 10.1177/1740774509344778 ( Abstract ) Google Scholar Citation Count: 17 (03/28/0024) iCite Citation Count: 5 and iCite RCR: 0.13 (04/01/2024) OpenCitations Citation Count: 5 (04/01/2024)

17.   Fong LY, Jiang Y, Riley M, Liu X, Smalley KJ, Guttridge DC, Farber JL. Prevention of upper aerodigestive tractc ancer in zinc-deficient rodents: Inefficacy of genetic or pharmacological disruption of COX-2. Int J Cancer. 2008 Mar1;122(5):978-89. PMID: 17985342 PMCID: PMC2679643 DOI: 10.1002/ijc.23221 ( Abstract ) Google Scholar Citation Count: 18 (03/28/0024) iCite Citation Count: 14 and iCite RCR: 0.39 (04/01/2024) OpenCitations Citation Count: 13 (04/01/2024)

16.   London JW, Marshall A, Talarico R, Miller C, Conner K, Smalley KJ, Smith JB. Poster Presentation. The Design and Implementation of a Fully Automated Adverse Event Reporting System. 2006 Annual Human Research Protection Programs (HRPP) Conference. Washington DC, November 15-18 2006. ( Abstract ) ( Poster )

15.   Li F, Yang J, Smalley KJ, Warzel D, London JW. Poster Presentation: Local Cancer Centers Legacy Adoption Strategy For CaBIG Projects, NCI caBIG (cancer Biomedical Informatics Grid) 2006 Annual Meeting, Arlington, VA. April 9-11, 2006. ( Poster )

14.   Li F, Smalley KJ, London JW. Poster Presentation: The Challenges of Integrating caGRID in the Cancer Center Environment, NCI caBIG (cancer Biomedical Informatics Grid) 2006 Annual Meeting, Arlington, VA. April 9-11, 2006. ( Abstract ) ( Poster )

13.   Li F, Smalley KJ, London JW. Poster Presentation: Adapting caArray to a Cancer Center's Workflow, NCI caBIG (cancerBiomedical Informatics Grid) 2005 Annual Meeting, Bethesda, MD. April 12-13, 2005. ( Abstract ) ( Poster )

12.   Owen OE, Smalley KJ, Jungas RL. Chapter: Starvation. In: Handbook of Physiology. Section 7: The Endocrine System, Vol. 2: The Endocrine Pancreas and Regulation of Metabolism. Edited by L.S. Jefferson and A.D.Cherrington. Oxford University Press. 2001; Ch. 39, 1199-225. Google Scholar Citation Count: 20 (03/28/0024)

11.   A. No, M. Mahoney, A. Simpson, U. Rodeck, M. Jost, K.J. Smalley, J. Mulholland. Poster Presentation: Matrilysin and invasiveness of squamous cell carcinoma cell lines. The first symposium of the international society for matrix biology, Jefferson Medical College, Philadelphia, PA. June 14-17, 2000.

10.   Owen OE, Smalley KJ, D'Alessio DA, Mozzoli MA, Dawson EK. Protein, fat, and carbohydrate requirements during starvation: anaplerosis and cataplerosis. Am J Clin Nutr. 1998; 68(1):12-34. PMID: 9665093 DOI: 10.1093/ajcn/68.1.12 ( Abstract ) Google Scholar Citation Count: 164 (03/28/0024) iCite Citation Count: 80 and iCite RCR: 2.10 (04/01/2024) OpenCitations Citation Count: 76 (04/01/2024)

9.   Owen OE, Mozzoli MA, Smalley KJ, D'Alessio DA. Oxidative and nonoxidative macronutrient disposal in lean and obese men following mixed meals. Am J Clin Nutr. 1992; 55:630-6. PMID: 1550035 DOI: 10.1093/ajcn/55.3.630 ( Abstract ) Google Scholar Citation Count: 9 (03/28/0024) iCite Citation Count: 4 and iCite RCR: 0.19 (04/01/2024) OpenCitations Citation Count: 4 (04/01/2024)

8.   Owen OE, Smalley KJ, Mozzoli MA, Polansky M. Urinary nitrogen excretion, body composition, gender, and resting metabolic rate in healthy humans. Clin Res. 1990; 38:338A. Google Scholar Citation Count: 3 (03/28/0024)

7.   Smalley KJ, Knerr AN, Colliver JA, Owen OE. A reassessment of body mass indices. Am J Clin Nutr. 1990; 52:405-408. PMID: 2393001 DOI: 10.1093/ajcn/52.3.405 ( Abstract ) Google Scholar Citation Count: 489 (03/28/0024) iCite Citation Count: 209 and iCite RCR: 8.47 (04/01/2024) OpenCitations Citation Count: 201 (04/01/2024)

6.   Owen OE, Smalley KJ, D'Alessio DA, Mozzoli MA, Knerr AN, Kendrick ZV, Kavle EC, Donohue M, Tappy L, Boden G. Resting metabolic rate and body composition of achondroplastic dwarfs. Medicine. 1990; 69:56-67. PMID: 2299977 DOI: 10.1097/00005792-199001000-00005 ( Abstract ) Google Scholar Citation Count: 64 (03/28/0024) iCite Citation Count: 39 and iCite RCR: 1.72 (04/01/2024) OpenCitations Citation Count: 36 (04/01/2024)

5.   Comerota AJ, Stewart GJ, Alburger PD, Smalley K, White JV. Operative Venodilation: a previously unsuspected factoring etiology of postoperative deep vein thrombosis. Surgery. 1990; 106:301-9. PMID: 2763031 ( Abstract ) Google Scholar Citation Count: 163 (03/28/0024) iCite Citation Count: 100 and iCite RCR: 4.37 (04/01/2024) OpenCitations Citation Count: 99 (04/01/2024)

4.   Owen OE, Tappy L, Mozzoli MA, Smalley KJ. Chapter: Acute Starvation. In: The Metabolic and Molecular Basis of Acquired Disease. Edited by R.D. Cohen, K.G.M.M. Alberti, B. Lewis and A.M. Derman. Bailliere Tindall, London. 1990; 550-70. Google Scholar Citation Count: 25 (03/28/0024)

3.   D'Alessio DA, Kavle EC, Mozzoli MA, Smalley KJ, Polansky M, Kendrick ZV, Owen LR, Bushman MC, Boden G, Owen OE. Thermic effect of food in lean and obese men. J Clin Invest. 1988; 81:1781-1789. PMID: 3384951 PMCID: PMC442625 DOI: 10.1172/JCI113520 ( Abstract ) Google Scholar Citation Count: 249 (03/28/0024) iCite Citation Count: 146 and iCite RCR: 5.50 (04/01/2024) OpenCitations Citation Count: 145 (04/01/2024)

2.   Owen OE, Holup JL, D'Alessio DA, Craig ES, Polansky M, Smalley KJ, Kavle EC, Bushman MC, Owen LR, Mozzoli MA, Kendrick ZV, Boden GH. A reappraisal of the caloric requirements of men. Am J Clin Nutr. 1987; 46:875-885. PMID: 3687821 DOI: 10.1093/ajcn/46.6.875 ( Abstract ) Google Scholar Citation Count: 498 (03/28/0024) iCite Citation Count: 279 and iCite RCR: 13.35 (03/01/2024) OpenCitations Citation Count: 266 (04/01/2024)

1.   Owen OE, Holup JL, D'Alessio DA, Craig ES, Polansky M, Smalley KJ, Kavle EC, Bushman MC, Owen LR, Mozzoli MA, Kendrick ZV, Boden GH. A reappraisal of the caloric requirements of men. Clin.Res. 1987; 35:644A.



Average Google Citation Count (2165/22): 98.41     Google Scholar h-index: 17

Average iCite Citation Count (1191/19): 62.68     Average iCite Relative Citation Rate (47.63/18): 2.65     iCite h-index: 14

Average Open Citations Citation Count (1123/18): 62.39     Open Citations h-index: 13


MyNCBI: https://www.ncbi.nlm.nih.gov/myncbi/karl.smalley.1/bibliography/public/

Google Scholar: https://scholar.google.com/citations?user=eaM86QkAAAAJ&hl=en

Google Scholar Citation Counts maintained manually from link above.
iCite Citation Data (Count and Relative Citation Rate) loaded automatically (monthly) from https://icite.od.nih.gov/
OpenCitations Citation Count loaded automatically (monthly) from https://opencitations.net/

 

Web page revised: December 22, 2023
URL: https://ewebapp01pa.jefferson.edu/smalley/



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